high frequency oscillatory ventilation in severe respiratory failure

نویسندگان

فیروزه نیلی

nili f

چکیده

despite improvement of mechanical ventilation devices for infants, lung injury still causes morbidity and mortality in many cases. to determine the effect of high frequency oscillatory ventilation (hfov) in infants with severe respiratory failure, 10 neonates were evaluated prospectively. mean gestational age of these patients was 35 weeks and alveolar-arterial oxygen gradient (a-ado2) and the ratio of arterial to alveolar oxygen pressure (a/a) immediately before hfo were 610 torr and 0.072 respectively. these neonates were received inspired oxygen concentration of >95% with a mean airway pressure of 12 cm h2o by conventional mechanical ventilation. the a-ado2 and a/a after 6 and 24 hrs on hfo was not significant in those infants with survived compared with those who died. comparison of 3 alive neonates with 7 deaths, demonstrate that pulmonary hypoplasia, hmd accompanied with asphyxia, congestive heart failure with pneumonia are associated with poor outcome. the mean a/a ratio during 24hrs of hfo in the alived hmd group was 0.75 compared with 0.25 in those who died. it is possible that we can use this as a prognostic factor in survival. in this study, the positive effect of hfov was demonstrated in those with no predisposing factors such as pulmonary hypoplasia, congestive heart failure, pneumonia and asphyxia.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure.

OBJECTIVE To compare the effectiveness of high-frequency oscillatory ventilation with conventional mechanical ventilation in pediatric patients with respiratory failure. SETTING Five tertiary care pediatric intensive care units. DESIGN A prospective, randomized, clinical study with crossover. PATIENTS Seventy patients with either diffuse alveolar disease and/or airleak syndrome were rando...

متن کامل

Respiratory input impedance during high frequency oscillatory ventilation.

Total respiratory input impedance (Zrs) measured by forced excitation may be computed easily from pressure and flow measurements recorded at the airway opening. The purpose of this paper was to analyse how the information provided by Zrs may be used for monitoring ventilatory mechanics during high frequency oscillatory ventilation (HFOV). We measured impedance (0.125-32 Hz) in six dogs, and in ...

متن کامل

High-frequency oscillatory ventilation for acute respiratory distress syndrome.

OBJECTIVE To evaluate the effectiveness of HFOV in pediatric patients with acute respiratory distress syndrome. METHODS In this retrospective study, we reviewed all 20 pediatric patients, who were consecutively ventilated with HFOV in the pediatric intensive care unit of a tertiary medical center, from January 2006 to February 2007. RESULTS A total of 20 patients were enrolled. The median a...

متن کامل

High-frequency oscillatory ventilation versus synchronized intermittent mandatory ventilation plus pressure support in preterm infants with severe respiratory distress syndrome.

BACKGROUND Mechanical ventilation and surfactants are the standard treatment of preterm respiratory distress syndrome (RDS). The effects of the primary ventilation model on bronchopulmonary dysplasia (BPD) and long-term neurodevelopment outcomes are controversial. The purpose of this study was to compare the efficacy and safety of high-frequency oscillatory ventilation (HFOV) and synchronized i...

متن کامل

High-frequency oscillatory ventilation in pediatric patients.

HFOV is a mode of ventilation that can achieve oxygenation and ventilation while maintaining maximal lung recruitment on the deflation limb of its pressure-volume curve. The primary theoretical advantages of HFOV over CMV in the management of acute lung injury are that HFOV allows adequate alveolar ventilation with minimal peak-trough pressure changes, provides lung recruitment, and avoids end-...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران

جلد ۵۸، شماره ۳، صفحات ۲۹-۳۴

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023